The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism

Immune cells are somewhat unique in that activation responses can alter quantitative phenotypes upwards of 100,000-fold. To date little is known about the metabolic adaptations necessary to mount such dramatic phenotypic shifts. Screening for novel regulators of macrophage activation, we found nonpr...

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Detalles Bibliográficos
Autores principales: Haschemi, Arvand, Kosma, Paul, Gille, Lars, Evans, Charles R., Burant, Charles F., Starkl, Philipp, Knapp, Bernhard, Haas, Robert, Schmid, Johannes A., Jandl, Christoph, Amir, Shahzada, Lubec, Gert, Park, Jaehong, Esterbauer, Harald, Bilban, Martin, Brizuela, Leonardo, Pospisilik, J. Andrew, Otterbein, Leo E., Wagner, Oswald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370649/
https://www.ncbi.nlm.nih.gov/pubmed/22682222
http://dx.doi.org/10.1016/j.cmet.2012.04.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370649/
https://www.ncbi.nlm.nih.gov/pubmed/22682222
http://dx.doi.org/10.1016/j.cmet.2012.04.023

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