Cargando…

The Shear Stress-Induced Transcription Factor KLF2 Affects Dynamics and Angiopoietin-2 Content of Weibel-Palade Bodies

BACKGROUND: The shear-stress induced transcription factor KLF2 has been shown to induce an atheroprotective phenotype in endothelial cells (EC) that are exposed to prolonged laminar shear. In this study we characterized the effect of the shear stress-induced transcription factor KLF2 on regulation a...

Descripción completa

Detalles Bibliográficos
Autores principales: van Agtmaal, Ellen L., Bierings, Ruben, Dragt, Bieuwke S., Leyen, Thomas A., Fernandez-Borja, Mar, Horrevoets, Anton J. G., Voorberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371018/
https://www.ncbi.nlm.nih.gov/pubmed/22715381
http://dx.doi.org/10.1371/journal.pone.0038399