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Inhibition of Fibroblast Growth by Notch1 Signaling Is Mediated by Induction of Wnt11-Dependent WISP-1

Fibroblasts are an integral component of stroma and important source of growth factors and extracellular matrix (ECM). They play a prominent role in maintaining tissue homeostasis and in wound healing and tumor growth. Notch signaling regulates biological function in a variety of cells. To elucidate...

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Detalles Bibliográficos
Autores principales: Liu, Zhao-Jun, Li, Yan, Tan, Yurong, Xiao, Min, Zhang, Jialin, Radtke, Freddy, Velazquez, Omaida C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371022/
https://www.ncbi.nlm.nih.gov/pubmed/22715413
http://dx.doi.org/10.1371/journal.pone.0038811