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High Quality Long-Term CD4(+) and CD8(+) Effector Memory Populations Stimulated by DNA-LACK/MVA-LACK Regimen in Leishmania major BALB/c Model of Infection

Heterologous vaccination based on priming with a plasmid DNA vector and boosting with an attenuated vaccinia virus MVA recombinant, with both vectors expressing the Leishmania infantum LACK antigen (DNA-LACK and MVA-LACK), has shown efficacy conferring protection in murine and canine models against...

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Detalles Bibliográficos
Autores principales: Sánchez-Sampedro, Lucas, Gómez, Carmen Elena, Mejías-Pérez, Ernesto, S. Sorzano, Carlos Oscar, Esteban, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371028/
https://www.ncbi.nlm.nih.gov/pubmed/22715418
http://dx.doi.org/10.1371/journal.pone.0038859