Cargando…

Reduced Surface Expression of Epithelial E-Cadherin Evoked by Interferon-Gamma Is Fyn Kinase-Dependent

Interferon gamma (IFNγ) is an important regulatory cytokine that can exert a pro-inflammatory effect in the gut, where it has been shown to increase epithelial permeability via disruption of the tight junctions. Here we investigated the potential for IFNγ to regulate the adherens junction protein E-...

Descripción completa

Detalles Bibliográficos
Autores principales: Smyth, David, Leung, Gabriella, Fernando, Maria, McKay, Derek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371038/
https://www.ncbi.nlm.nih.gov/pubmed/22715382
http://dx.doi.org/10.1371/journal.pone.0038441