Consensus Rules in Variant Detection from Next-Generation Sequencing Data

A critical step in detecting variants from next-generation sequencing data is post hoc filtering of putative variants called or predicted by computational tools. Here, we highlight four critical parameters that could enhance the accuracy of called single nucleotide variants and insertions/deletions:...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Peilin, Li, Fei, Xia, Jufeng, Chen, Haiquan, Ji, Hongbin, Pao, William, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371040/
https://www.ncbi.nlm.nih.gov/pubmed/22715385
http://dx.doi.org/10.1371/journal.pone.0038470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371040/
https://www.ncbi.nlm.nih.gov/pubmed/22715385
http://dx.doi.org/10.1371/journal.pone.0038470

Ejemplares similares