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Inhibition of Biofilm Formation, Quorum Sensing and Infection in Pseudomonas aeruginosa by Natural Products-Inspired Organosulfur Compounds

Using a microplate-based screening assay, the effects on Pseudomonas aeruginosa PAO1 biofilm formation of several S-substituted cysteine sulfoxides and their corresponding disulfide derivatives were evaluated. From our library of compounds, S-phenyl-L-cysteine sulfoxide and its breakdown product, di...

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Detalles Bibliográficos
Autores principales: Cady, Nathaniel C., McKean, Kurt A., Behnke, Jason, Kubec, Roman, Mosier, Aaron P., Kasper, Stephen H., Burz, David S., Musah, Rabi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371053/
https://www.ncbi.nlm.nih.gov/pubmed/22715388
http://dx.doi.org/10.1371/journal.pone.0038492