Cargando…

Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect

Inadvertent mammalian tissue exposures to low doses of ionizing radiation (IR) after radiation accidents, remediation of radioactive-contaminated areas, space travel, or a dirty bomb represents an interesting trauma to an organism. Possible low dose IR-induced bystander effects could impact our eval...

Descripción completa

Detalles Bibliográficos
Autores principales: Klokov, Dmitry, Leskov, Konstantin, Araki, Shinako, Zou, Yonglong, Goetz, Eva M., Luo, Xiuquan, Willson, David, Boothman, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371099/
https://www.ncbi.nlm.nih.gov/pubmed/22391565
http://dx.doi.org/10.1038/onc.2012.64