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Antibodies against cyclic citrullinated peptides of IgG, IgA and IgM isotype and rheumatoid factor of IgM and IgA isotype are increased in unaffected members of multicase rheumatoid arthritis families from northern Sweden

BACKGROUND: Rheumatoid factors (RFs) and antibodies against cyclic citrullinated peptides (CCPs) of IgG, IgA and IgM isotype have been shown to precede disease onset by years. OBJECTIVE: To evaluate serological risk markers in first-degree relatives from multicase families in relation to genetic and...

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Detalles Bibliográficos
Autores principales: Ärlestig, Lisbeth, Mullazehi, Mohammed, Kokkonen, Heidi, Rocklöv, Joacim, Rönnelid, Johan, Dahlqvist, Solbritt Rantapää
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371219/
https://www.ncbi.nlm.nih.gov/pubmed/22128080
http://dx.doi.org/10.1136/annrheumdis-2011-200668