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CCN1 Induces β-Catenin Translocation in Esophageal Squamous Cell Carcinoma through Integrin α11

Aims. Nuclear translocation of β-catenin is common in many cancers including esophageal squamous cell carcinoma (ESCC). As a mediator of Wnt signaling pathway, nuclear β-catenin can activate many growth-related genes including CCN1, which in turn can induce β-catenin translocation. CCN1, a matricell...

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Detalles Bibliográficos
Autores principales: Chai, Jianyuan, Modak, Cristina, Ouyang, Yi, Wu, Sing-Yung, Jamal, M. Mazen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371350/
https://www.ncbi.nlm.nih.gov/pubmed/22701179
http://dx.doi.org/10.5402/2012/207235