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A quantitative atlas of polyadenylation in five mammals

We developed PolyA-seq, a strand-specific and quantitative method for high-throughput sequencing of 3′ ends of polyadenylated transcripts, and used it to globally map polyadenylation (polyA) sites in 24 matched tissues in human, rhesus, dog, mouse, and rat. We show that PolyA-seq is as accurate as e...

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Detalles Bibliográficos
Autores principales: Derti, Adnan, Garrett-Engele, Philip, MacIsaac, Kenzie D., Stevens, Richard C., Sriram, Shreedharan, Chen, Ronghua, Rohl, Carol A., Johnson, Jason M., Babak, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371698/
https://www.ncbi.nlm.nih.gov/pubmed/22454233
http://dx.doi.org/10.1101/gr.132563.111