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BRAF(V600E) remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration

Aberrations of protein-coding genes are a focus of cancer genomics; however, the impact of oncogenes on expression of the ∼50% of transcripts without protein-coding potential, including long noncoding RNAs (lncRNAs), has been largely uncharacterized. Activating mutations in the BRAF oncogene are pre...

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Detalles Bibliográficos
Autores principales: Flockhart, Ross J., Webster, Dan E., Qu, Kun, Mascarenhas, Nicholas, Kovalski, Joanna, Kretz, Markus, Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371703/
https://www.ncbi.nlm.nih.gov/pubmed/22581800
http://dx.doi.org/10.1101/gr.140061.112