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H2B monoubiquitylation is a 5′-enriched active transcription mark and correlates with exon–intron structure in human cells

H2B monoubiquitylation (H2Bub1), which is required for multiple methylations of both H3K4 and H3K79, has been implicated in gene expression in numerous organisms ranging from yeast to human. However, the molecular crosstalk between H2Bub1 and other modifications, especially the methylations of H3K4...

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Detalles Bibliográficos
Autores principales: Jung, Inkyung, Kim, Seung-Kyoon, Kim, Mirang, Han, Yong-Mahn, Kim, Yong Sung, Kim, Dongsup, Lee, Daeyoup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371706/
https://www.ncbi.nlm.nih.gov/pubmed/22421545
http://dx.doi.org/10.1101/gr.120634.111