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H2B monoubiquitylation is a 5′-enriched active transcription mark and correlates with exon–intron structure in human cells
H2B monoubiquitylation (H2Bub1), which is required for multiple methylations of both H3K4 and H3K79, has been implicated in gene expression in numerous organisms ranging from yeast to human. However, the molecular crosstalk between H2Bub1 and other modifications, especially the methylations of H3K4...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371706/ https://www.ncbi.nlm.nih.gov/pubmed/22421545 http://dx.doi.org/10.1101/gr.120634.111 |