Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung

Asthma pathogenesis is focused around conducting airways. The reasons for this focus have been unclear because it has not been possible to track the sites and timing of antigen uptake or subsequent antigen presentation to effector T cells. In this study, we use two-photon microscopy of the lung pare...

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Detalles Bibliográficos
Autores principales: Thornton, Emily E., Looney, Mark R., Bose, Oishee, Sen, Debasish, Sheppard, Dean, Locksley, Richard, Huang, Xiaozhu, Krummel, Matthew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371730/
https://www.ncbi.nlm.nih.gov/pubmed/22585735
http://dx.doi.org/10.1084/jem.20112667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371730/
https://www.ncbi.nlm.nih.gov/pubmed/22585735
http://dx.doi.org/10.1084/jem.20112667

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