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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

Certain types of nonpsychoactive cannabinoids can potentiate glycine receptors (GlyRs), an important target for nociceptive regulation at the spinal level. However, little is known about the potential and mechanism of glycinergic cannabinoids for chronic pain treatment. We report that systemic and i...

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Detalles Bibliográficos
Autores principales: Xiong, Wei, Cui, Tanxing, Cheng, Kejun, Yang, Fei, Chen, Shao-Rui, Willenbring, Dan, Guan, Yun, Pan, Hui-Lin, Ren, Ke, Xu, Yan, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371734/
https://www.ncbi.nlm.nih.gov/pubmed/22585736
http://dx.doi.org/10.1084/jem.20120242