Rapamycin increases oxidative stress response gene expression in adult stem cells

Balancing quiescence with proliferation is of paramount importance for adult stem cells in order to avoid hyperproliferation and cell depletion. In some models, stem cell exhaustion may be reversed with the drug rapamycin, which was shown can suppress cellular senescence in vitro and extend lifespan...

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Detalles Bibliográficos
Autores principales: Kofman, Amber E., McGraw, Margeaux R., Payne, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371763/
https://www.ncbi.nlm.nih.gov/pubmed/22529334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371763/
https://www.ncbi.nlm.nih.gov/pubmed/22529334

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