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A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements

BACKGROUND: High-throughput sequencing is becoming the standard tool for investigating protein-DNA interactions or epigenetic modifications. However, the data generated will always contain noise due to e.g. repetitive regions or non-specific antibody interactions. The noise will appear in the form o...

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Detalles Bibliográficos
Autores principales: Enroth, Stefan, Andersson, Claes R, Andersson, Robin, Wadelius, Claes, Gustafsson, Mats G, Komorowski, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371767/
https://www.ncbi.nlm.nih.gov/pubmed/22248020
http://dx.doi.org/10.1186/1748-7188-7-2