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Recognition models to predict DNA-binding specificities of homeodomain proteins
Motivation: Recognition models for protein-DNA interactions, which allow the prediction of specificity for a DNA-binding domain based only on its sequence or the alteration of specificity through rational design, have long been a goal of computational biology. There has been some progress in constru...
Autores principales: | Christensen, Ryan G., Enuameh, Metewo Selase, Noyes, Marcus B., Brodsky, Michael H., Wolfe, Scot A., Stormo, Gary D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371834/ https://www.ncbi.nlm.nih.gov/pubmed/22689783 http://dx.doi.org/10.1093/bioinformatics/bts202 |
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