Lineage-based identification of cellular states and expression programs

Summary: We present a method, LineageProgram, that uses the developmental lineage relationship of observed gene expression measurements to improve the learning of developmentally relevant cellular states and expression programs. We find that incorporating lineage information allows us to significant...

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Detalles Bibliográficos
Autores principales: Hashimoto, Tatsunori, Jaakkola, Tommi, Sherwood, Richard, Mazzoni, Esteban O., Wichterle, Hynek, Gifford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Ismb 2012 Proceedings Papers Committee July 15 to July 19, 2012, Long Beach, Ca, Usa
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371836/
https://www.ncbi.nlm.nih.gov/pubmed/22689769
http://dx.doi.org/10.1093/bioinformatics/bts204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371836/
https://www.ncbi.nlm.nih.gov/pubmed/22689769
http://dx.doi.org/10.1093/bioinformatics/bts204

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