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Weighted pooling—practical and cost-effective techniques for pooled high-throughput sequencing
Motivation: Despite the rapid decline in sequencing costs, sequencing large cohorts of individuals is still prohibitively expensive. Recently, several sophisticated pooling designs were suggested that can identify carriers of rare alleles in large cohorts with a significantly smaller number of pools...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371840/ https://www.ncbi.nlm.nih.gov/pubmed/22689761 http://dx.doi.org/10.1093/bioinformatics/bts208 |