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Detection of allele-specific methylation through a generalized heterogeneous epigenome model
Motivations: High-throughput sequencing has made it possible to sequence DNA methylation of a whole genome at the single-base resolution. A sample, however, may contain a number of distinct methylation patterns. For instance, cells of different types and in different developmental stages may have di...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371863/ https://www.ncbi.nlm.nih.gov/pubmed/22689757 http://dx.doi.org/10.1093/bioinformatics/bts231 |