PSI-Search: iterative HOE-reduced profile SSEARCH searching

Summary: Iterative similarity searches with PSI-BLAST position-specific score matrices (PSSMs) find many more homologs than single searches, but PSSMs can be contaminated when homologous alignments are extended into unrelated protein domains—homologous over-extension (HOE). PSI-Search combines an op...

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Detalles Bibliográficos
Autores principales: Li, Weizhong, McWilliam, Hamish, Goujon, Mickael, Cowley, Andrew, Lopez, Rodrigo, Pearson, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371869/
https://www.ncbi.nlm.nih.gov/pubmed/22539666
http://dx.doi.org/10.1093/bioinformatics/bts240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371869/
https://www.ncbi.nlm.nih.gov/pubmed/22539666
http://dx.doi.org/10.1093/bioinformatics/bts240

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