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Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli
The biochemical and physical factors controlling protein expression level and solubility in vivo remain incompletely characterized. To gain insight into the primary sequence features influencing these outcomes, we performed statistical analyses of results from the high-throughput protein-production...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372292/ https://www.ncbi.nlm.nih.gov/pubmed/22587847 http://dx.doi.org/10.1186/2042-5783-1-6 |