Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli

The biochemical and physical factors controlling protein expression level and solubility in vivo remain incompletely characterized. To gain insight into the primary sequence features influencing these outcomes, we performed statistical analyses of results from the high-throughput protein-production...

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Detalles Bibliográficos
Autores principales: Price, W Nicholson, Handelman, Samuel K, Everett, John K, Tong, Saichiu N, Bracic, Ana, Luff, Jon D, Naumov, Victor, Acton, Thomas, Manor, Philip, Xiao, Rong, Rost, Burkhard, Montelione, Gaetano T, Hunt, John F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372292/
https://www.ncbi.nlm.nih.gov/pubmed/22587847
http://dx.doi.org/10.1186/2042-5783-1-6

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