Generalized adjacency and the conservation of gene clusters in genetic networks defined by synthetic lethals

BACKGROUND: Given genetic networks derived from two genomes, it may be difficult to decide if their local structures are similar enough in both genomes to infer some ancestral configuration or some conserved functional relationships. Current methods all depend on searching for identical substructure...

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Detalles Bibliográficos
Autores principales: Yang, Zhenyu, Sankoff, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372455/
https://www.ncbi.nlm.nih.gov/pubmed/22901093
http://dx.doi.org/10.1186/1471-2105-13-S9-S8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372455/
https://www.ncbi.nlm.nih.gov/pubmed/22901093
http://dx.doi.org/10.1186/1471-2105-13-S9-S8

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