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Generalized adjacency and the conservation of gene clusters in genetic networks defined by synthetic lethals
BACKGROUND: Given genetic networks derived from two genomes, it may be difficult to decide if their local structures are similar enough in both genomes to infer some ancestral configuration or some conserved functional relationships. Current methods all depend on searching for identical substructure...
Autores principales: | Yang, Zhenyu, Sankoff, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372455/ https://www.ncbi.nlm.nih.gov/pubmed/22901093 http://dx.doi.org/10.1186/1471-2105-13-S9-S8 |
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