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A novel method to identify high order gene-gene interactions in genome-wide association studies: Gene-based MDR

BACKGROUND: Because common complex diseases are affected by multiple genes and environmental factors, it is essential to investigate gene-gene and/or gene-environment interactions to understand genetic architecture of complex diseases. After the great success of large scale genome-wide association (...

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Detalles Bibliográficos
Autores principales: Oh, Sohee, Lee, Jaehoon, Kwon, Min-Seok, Weir, Bruce, Ha, Kyooseob, Park, Taesung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372457/
https://www.ncbi.nlm.nih.gov/pubmed/22901090
http://dx.doi.org/10.1186/1471-2105-13-S9-S5