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Antioxidant Protects against Increases in Low Molecular Weight Hyaluronan and Inflammation in Asphyxiated Newborn Pigs Resuscitated with 100% Oxygen

BACKGROUND: Newborn resuscitation with 100% oxygen is associated with oxidative-nitrative stresses and inflammation. The mechanisms are unclear. Hyaluronan (HA) is fragmented to low molecular weight (LMW) by oxidative-nitrative stresses and can promote inflammation. We examined the effects of 100% o...

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Detalles Bibliográficos
Autores principales: Østerholt, Helene C. D., Dannevig, Ingrid, Wyckoff, Myra H., Liao, Jie, Akgul, Yucel, Ramgopal, Mrithyunjay, Mija, Dan S., Cheong, Naeun, Longoria, Christopher, Mahendroo, Mala, Nakstad, Britt, Saugstad, Ola D., Savani, Rashmin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372475/
https://www.ncbi.nlm.nih.gov/pubmed/22701723
http://dx.doi.org/10.1371/journal.pone.0038839