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Tumor Progression Locus 2 (Tpl2) Deficiency Does Not Protect against Obesity-Induced Metabolic Disease

Obesity is associated with a state of chronic low grade inflammation that plays an important role in the development of insulin resistance. Tumor progression locus 2 (Tpl2) is a serine/threonine mitogen activated protein kinase kinase kinase (MAP3K) involved in regulating responses to specific infla...

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Detalles Bibliográficos
Autores principales: Lancaster, Graeme I., Kowalski, Greg M., Estevez, Emma, Kraakman, Michael J., Grigoriadis, George, Febbraio, Mark A., Gerondakis, Steve, Banerjee, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372481/
https://www.ncbi.nlm.nih.gov/pubmed/22701749
http://dx.doi.org/10.1371/journal.pone.0039100