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Tumor Progression Locus 2 (Tpl2) Deficiency Does Not Protect against Obesity-Induced Metabolic Disease
Obesity is associated with a state of chronic low grade inflammation that plays an important role in the development of insulin resistance. Tumor progression locus 2 (Tpl2) is a serine/threonine mitogen activated protein kinase kinase kinase (MAP3K) involved in regulating responses to specific infla...
Autores principales: | Lancaster, Graeme I., Kowalski, Greg M., Estevez, Emma, Kraakman, Michael J., Grigoriadis, George, Febbraio, Mark A., Gerondakis, Steve, Banerjee, Ashish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372481/ https://www.ncbi.nlm.nih.gov/pubmed/22701749 http://dx.doi.org/10.1371/journal.pone.0039100 |
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