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Caffeine Reduces 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in Human Trophoblast Cells through the Adenosine A(2B) Receptor

Maternal caffeine consumption is associated with reduced fetal growth, but the underlying molecular mechanisms are unknown. Since there is evidence that decreased placental 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) is linked to fetal growth restriction, we hypothesized that caffeine may inh...

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Detalles Bibliográficos
Autores principales: Sharmin, Saina, Guan, Haiyan, Williams, Andrew Scott, Yang, Kaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372487/
https://www.ncbi.nlm.nih.gov/pubmed/22701600
http://dx.doi.org/10.1371/journal.pone.0038082