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Hyaluronan Export through Plasma Membranes Depends on Concurrent K(+) Efflux by K(ir) Channels

Hyaluronan is synthesized within the cytoplasm and exported into the extracellular matrix through the cell membrane of fibroblasts by the MRP5 transporter. In order to meet the law of electroneutrality, a cation is required to neutralize the emerging negative hyaluronan charges. As we previously obs...

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Detalles Bibliográficos
Autores principales: Hagenfeld, Daniel, Borkenhagen, Beatrice, Schulz, Tobias, Schillers, Hermann, Schumacher, Udo, Prehm, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372488/
https://www.ncbi.nlm.nih.gov/pubmed/22701748
http://dx.doi.org/10.1371/journal.pone.0039096