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Hyaluronan Export through Plasma Membranes Depends on Concurrent K(+) Efflux by K(ir) Channels
Hyaluronan is synthesized within the cytoplasm and exported into the extracellular matrix through the cell membrane of fibroblasts by the MRP5 transporter. In order to meet the law of electroneutrality, a cation is required to neutralize the emerging negative hyaluronan charges. As we previously obs...
Autores principales: | Hagenfeld, Daniel, Borkenhagen, Beatrice, Schulz, Tobias, Schillers, Hermann, Schumacher, Udo, Prehm, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372488/ https://www.ncbi.nlm.nih.gov/pubmed/22701748 http://dx.doi.org/10.1371/journal.pone.0039096 |
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