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Reduction of Hox Gene Expression by Histone H1 Depletion

The evolutionarily conserved homeotic (Hox) genes are organized in clusters and expressed collinearly to specify body patterning during embryonic development. Chromatin reorganization and decompaction are intimately connected with Hox gene activation. Linker histone H1 plays a key role in facilitati...

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Detalles Bibliográficos
Autores principales: Zhang, Yunzhe, Liu, Zheng, Medrzycki, Magdalena, Cao, Kaixiang, Fan, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372500/
https://www.ncbi.nlm.nih.gov/pubmed/22701719
http://dx.doi.org/10.1371/journal.pone.0038829