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PARP16/ARTD15 Is a Novel Endoplasmic-Reticulum-Associated Mono-ADP-Ribosyltransferase That Interacts with, and Modifies Karyopherin-ß1

BACKGROUND: Protein mono-ADP-ribosylation is a reversible post-translational modification that modulates the function of target proteins. The enzymes that catalyze this reaction in mammalian cells are either bacterial pathogenic toxins or endogenous cellular ADP-ribosyltransferases. The latter inclu...

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Detalles Bibliográficos
Autores principales: Di Paola, Simone, Micaroni, Massimo, Di Tullio, Giuseppe, Buccione, Roberto, Di Girolamo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372510/
https://www.ncbi.nlm.nih.gov/pubmed/22701565
http://dx.doi.org/10.1371/journal.pone.0037352