Quercetin and Allopurinol Ameliorate Kidney Injury in STZ-Treated Rats with Regulation of Renal NLRP3 Inflammasome Activation and Lipid Accumulation

Hyperuricemia, hyperlipidemia and inflammation are associated with diabetic nephropathy. The NLRP3 inflammasome-mediated inflammation is recently recognized in the development of kidney injury. Urate and lipid are considered as danger signals in the NLRP3 inflammasome activation. Although dietary fl...

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Detalles Bibliográficos
Autores principales: Wang, Chuang, Pan, Ying, Zhang, Qing-Yu, Wang, Fu-Meng, Kong, Ling-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372527/
https://www.ncbi.nlm.nih.gov/pubmed/22701621
http://dx.doi.org/10.1371/journal.pone.0038285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372527/
https://www.ncbi.nlm.nih.gov/pubmed/22701621
http://dx.doi.org/10.1371/journal.pone.0038285

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