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The Centrosomal Kinase Plk1 Localizes to the Transition Zone of Primary Cilia and Induces Phosphorylation of Nephrocystin-1

Polo-like kinase (Plk1) plays a central role in regulating the cell cycle. Plk1-mediated phosphorylation is essential for centrosome maturation, and for numerous mitotic events. Although Plk1 localizes to multiple subcellular sites, a major site of action is the centrosomes, which supports mitotic f...

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Detalles Bibliográficos
Autores principales: Seeger-Nukpezah, Tamina, Liebau, Max C., Höpker, Katja, Lamkemeyer, Tobias, Benzing, Thomas, Golemis, Erica A., Schermer, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372538/
https://www.ncbi.nlm.nih.gov/pubmed/22701722
http://dx.doi.org/10.1371/journal.pone.0038838