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Transgenic Insights Linking Pitx2 and Atrial Arrhythmias

Pitx2 is a homeobox transcription factor involved in left–right signaling during embryogenesis. Disruption of left–right signaling in mice within its core nodal/lefty cascade, results in impaired expression of the last effector of the left–right cascade, Pitx2, leading in many cases to absence or bi...

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Detalles Bibliográficos
Autores principales: Franco, Diego, Chinchilla, Ana, Aránega, Amelia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372893/
https://www.ncbi.nlm.nih.gov/pubmed/22701438
http://dx.doi.org/10.3389/fphys.2012.00206