Reversing multidrug resistance in breast cancer cells by silencing ABC transporter genes with nanoparticle-facilitated delivery of target siRNAs

BACKGROUND: Multidrug resistance, a major impediment to successful cancer chemotherapy, is the result of overexpression of ATP-binding cassette (ABC) transporters extruding internalized drugs. Silencing of ABC transporter gene expression with small interfering RNA (siRNA) could be an attractive appr...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yong Tsuey, Chua, Ming Jang, Kunnath, Anil Philip, Chowdhury, Ezharul Hoque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373294/
https://www.ncbi.nlm.nih.gov/pubmed/22701315
http://dx.doi.org/10.2147/IJN.S30500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373294/
https://www.ncbi.nlm.nih.gov/pubmed/22701315
http://dx.doi.org/10.2147/IJN.S30500

Ejemplares similares