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Progressive dry-core-wet-rim hydration trend in a nested-ring topology of protein binding interfaces
BACKGROUND: Water is an integral part of protein complexes. It shapes protein binding sites by filling cavities and it bridges local contacts by hydrogen bonds. However, water molecules are usually not included in protein interface models in the past, and few distribution profiles of water molecules...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373366/ https://www.ncbi.nlm.nih.gov/pubmed/22452998 http://dx.doi.org/10.1186/1471-2105-13-51 |