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Progressive dry-core-wet-rim hydration trend in a nested-ring topology of protein binding interfaces

BACKGROUND: Water is an integral part of protein complexes. It shapes protein binding sites by filling cavities and it bridges local contacts by hydrogen bonds. However, water molecules are usually not included in protein interface models in the past, and few distribution profiles of water molecules...

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Detalles Bibliográficos
Autores principales: Li, Zhenhua, He, Ying, Wong, Limsoon, Li, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373366/
https://www.ncbi.nlm.nih.gov/pubmed/22452998
http://dx.doi.org/10.1186/1471-2105-13-51

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