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Integrity of the P-site is probed during maturation of the 60S ribosomal subunit

Eukaryotic ribosomes are preassembled in the nucleus and mature in the cytoplasm. Release of the antiassociation factor Tif6 by the translocase-like guanosine triphosphatase Efl1 is a critical late maturation step. In this paper, we show that a loop of Rpl10 that embraces the P-site transfer ribonuc...

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Detalles Bibliográficos
Autores principales: Bussiere, Cyril, Hashem, Yaser, Arora, Sucheta, Frank, Joachim, Johnson, Arlen W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373404/
https://www.ncbi.nlm.nih.gov/pubmed/22689654
http://dx.doi.org/10.1083/jcb.201112131