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Arginylation-dependent regulation of a proteolytic product of talin is essential for cell–cell adhesion
Talin is a large scaffolding molecule that plays a major role in integrin-dependent cell–matrix adhesion. A role for talin in cell–cell attachment through cadherin has never been demonstrated, however. Here, we identify a novel calpain-dependent proteolytic cleavage of talin that results in the rele...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373405/ https://www.ncbi.nlm.nih.gov/pubmed/22665520 http://dx.doi.org/10.1083/jcb.201112129 |