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An Evolutionarily Conserved Enhancer Regulates Bmp4 Expression in Developing Incisor and Limb Bud

To elucidate the transcriptional regulation of Bmp4 expression during organogenesis, we used phylogenetic footprinting and transgenic reporter analyses to identify Bmp4 cis-regulatory modules (CRMs). These analyses identified a regulatory region located ∼46 kb upstream of the mouse Bmp4 transcriptio...

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Detalles Bibliográficos
Autores principales: Jumlongras, Dolrudee, Lachke, Salil A., O’Connell, Daniel J., Aboukhalil, Anton, Li, Xiao, Choe, Sung E., Ho, Joshua W. K., Turbe-Doan, Annick, Robertson, Erin A., Olsen, Bjorn R., Bulyk, Martha L., Amendt, Brad A., Maas, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373496/
https://www.ncbi.nlm.nih.gov/pubmed/22701669
http://dx.doi.org/10.1371/journal.pone.0038568