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An Evolutionarily Conserved Enhancer Regulates Bmp4 Expression in Developing Incisor and Limb Bud
To elucidate the transcriptional regulation of Bmp4 expression during organogenesis, we used phylogenetic footprinting and transgenic reporter analyses to identify Bmp4 cis-regulatory modules (CRMs). These analyses identified a regulatory region located ∼46 kb upstream of the mouse Bmp4 transcriptio...
Autores principales: | Jumlongras, Dolrudee, Lachke, Salil A., O’Connell, Daniel J., Aboukhalil, Anton, Li, Xiao, Choe, Sung E., Ho, Joshua W. K., Turbe-Doan, Annick, Robertson, Erin A., Olsen, Bjorn R., Bulyk, Martha L., Amendt, Brad A., Maas, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373496/ https://www.ncbi.nlm.nih.gov/pubmed/22701669 http://dx.doi.org/10.1371/journal.pone.0038568 |
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