DCs Pulsed with Novel HLA-A2-Restricted CTL Epitopes against Hepatitis C Virus Induced a Broadly Reactive Anti-HCV-Specific T Lymphocyte Response

OBJECTIVE: To determine the capacity of dendritic cells (DCs) loaded with single or multiple-peptide mixtures of novel hepatitis C virus (HCV) epitopes to stimulate HCV-specific cytotoxic T lymphocyte (CTL) effector functions. METHODS: A bioinformatics approach was used to predict HLA-A2-restricted...

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Detalles Bibliográficos
Autores principales: Guo, Zhongsheng, Zhang, Henghui, Rao, Huiying, Jiang, Dong, Cong, Xu, Feng, Bo, Wang, Jianghua, Wei, Lai, Chen, Hongsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373515/
https://www.ncbi.nlm.nih.gov/pubmed/22701633
http://dx.doi.org/10.1371/journal.pone.0038390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373515/
https://www.ncbi.nlm.nih.gov/pubmed/22701633
http://dx.doi.org/10.1371/journal.pone.0038390

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