Cancer-Type Regulation of MIG-6 Expression by Inhibitors of Methylation and Histone Deacetylation

Epigenetic silencing is one of the mechanisms leading to inactivation of a tumor suppressor gene, either by DNA methylation or histone modification in a promoter regulatory region. Mitogen inducible gene 6 (MIG-6), mainly known as a negative feedback inhibitor of the epidermal growth factor receptor...

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Detalles Bibliográficos
Autores principales: Zhang, Yu-Wen, Staal, Ben, Dykema, Karl J., Furge, Kyle A., Vande Woude, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373526/
https://www.ncbi.nlm.nih.gov/pubmed/22701735
http://dx.doi.org/10.1371/journal.pone.0038955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373526/
https://www.ncbi.nlm.nih.gov/pubmed/22701735
http://dx.doi.org/10.1371/journal.pone.0038955

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