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Combined Multivariate and Pathway Analyses Show That Allergen-Induced Gene Expression Changes in CD4(+) T Cells Are Reversed by Glucocorticoids

BACKGROUND: Glucocorticoids (GCs) play a key role in the treatment of allergy. However, the genome-wide effects of GCs on gene expression in allergen-challenged CD4(+) T cells have not been described. The aim of this study was to perform a genome-wide analysis to investigate whether allergen-induced...

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Detalles Bibliográficos
Autores principales: Zhao, Yelin, Wang, Hui, Gustafsson, Mika, Muraro, Antonella, Bruhn, Sören, Benson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373548/
https://www.ncbi.nlm.nih.gov/pubmed/22701743
http://dx.doi.org/10.1371/journal.pone.0039016