LDL-Induced Impairment of Human Vascular Smooth Muscle Cells Repair Function Is Reversed by HMG-CoA Reductase Inhibition

Growing human atherosclerotic plaques show a progressive loss of vascular smooth muscle cells (VSMC) becoming soft and vulnerable. Lipid loaded-VSMC show impaired vascular repair function and motility due to changes in cytoskeleton proteins involved in cell-migration. Clinical benefits of statins re...

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Detalles Bibliográficos
Autores principales: Padró, Teresa, Lugano, Roberta, García-Arguinzonis, Maisa, Badimon, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373563/
https://www.ncbi.nlm.nih.gov/pubmed/22719992
http://dx.doi.org/10.1371/journal.pone.0038935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373563/
https://www.ncbi.nlm.nih.gov/pubmed/22719992
http://dx.doi.org/10.1371/journal.pone.0038935

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