Exposure to Candida albicans Polarizes a T-Cell Driven Arthritis Model towards Th17 Responses, Resulting in a More Destructive Arthritis

BACKGROUND: Fungal components have been shown very effective in generating Th17 responses. We investigated whether exposure to a minute amount of C. albicans in the arthritic joint altered the local cytokine environment, leading to enhanced Th17 expansion and resulting in a more destructive arthriti...

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Detalles Bibliográficos
Autores principales: Marijnissen, Renoud J., Koenders, Marije I., van de Veerdonk, Frank L., Dulos, John, Netea, Mihai G., Boots, Annemieke M.H., Joosten, Leo A.B., van den Berg, Wim B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373564/
https://www.ncbi.nlm.nih.gov/pubmed/22719976
http://dx.doi.org/10.1371/journal.pone.0038889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373564/
https://www.ncbi.nlm.nih.gov/pubmed/22719976
http://dx.doi.org/10.1371/journal.pone.0038889

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